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10.3390/metabo11010055 95

In addition, a comprehensive post-marketing surveillance system is critical for the ongoing detection and assessment of adverse events, enabling the rapid identification and management of safety concerns that may emerge after commercial release (564)

These conditions digestive conditions, such as Crohns disease and ulcerative colitis autoimmune conditions, such as celiac disease and type 1 diabetes genetic conditions, such as inherited intrinsic factor deficiency and inherited transcobalamin deficiency chronic pancreatic disease pernicious anemia vitiligo Other factors that may lead to a vitamin B12 deficiency can include drinking excessive amounts of alcohol or using certain drugs, such as some heartburn medicines and metformin

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This condition does not improve with splenectomy