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Cardiovascular Diabetology, 21
Recent studies of peptide-bound, active, Gs-coupled, structures of CTR or AMYRs provide evidence supporting distinct conformations of receptors when bound to CT peptides versus amylin peptides 15 that may contribute to pharmacological differences between dual CTR and AMYR agonists
This success rate is impressive relative to older therapies that tend to produce more modest results
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doi: 10.1111/dme.12726 32 IvanieviMHermanMHorvatiekMLovreni VuiMelmiJ
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