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Lapenna D, Pierdomenico SD, Ciofani G, et al

Mechano Growth Factor (MGF) is produced by skeletal muscle in response to mechanical loading, eccentric exercise, or injury through alternative splicing at exon 5 of the IGF-1 gene, generating a C-terminal extension peptide (the Ec peptide) that is unique to MGF and absent from systemic IGF-1

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The compound has a favorable safety profile, with few reported side effects in the available literature

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