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Approximately 95% of BAs are recycled via the hepatic circulation, controlled by fibroblast growth factor 15 and farnesoid X receptor (FXR) ( Figure 1 ) (Shin et al., 2013)

For weight management in adults without diabetes, NICE Technology Appraisals recommend: Liraglutide 3.0 mg (Saxenda) : For adults with a BMI of at least 35 kg/m (or at least 32.5 kg/m in people from certain ethnic groups) and at least one weight-related comorbidity, who are referred to and receiving specialist weight management services

The cafeteria diet used in our study creates an imbalance in the gut microbiota due to its high content of fat and sugar 50

Calculating exact amounts needed reduces waste and ensures each dose comes from freshly prepared solution

They are typically used alongside lifestyle changes