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35 Significant advances in pharmacological treatment have primarily focused on HFrEF, the current therapy for which is built on four key pillars: angiotensin receptorneprilysin inhibitor (ARNI) or, alternatively, ACE inhibitors or angiotensin receptor blockers

Menopause, Metabolic Changes, and Insulin Resistance

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Patients experiencing persistent or severe gastrointestinal symptoms should contact their GP or diabetes specialist nurse for advice

Like other common side effects, this tends to ease over time