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(PubMed) Kim SH, Shin MJ, Shin YB, Kim KU
CB-1158 could block myeloid cell-mediated inhibition of T cell proliferation, increase the number of tumor-infiltrating CD8 + T cells and NK cells, and increase the expression of inflammatory factors and interferon-, thereby changing the immune microenvironment to promote inflammation and reduce tumor immune escape, inhibiting tumor cell proliferation
These can be mild or severe
While PLE is not a standalone cure, it provides valuable support as part of a broader melasma treatment plan
[15] [16] Gastrointestinal symptoms may be misattributed to fatigue or may coexist with and contribute to tiredness
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