When to Contact Your PlexusDx Provider About Sweating Most sweating related to GLP-1 therapy is mild and self-limiting, but you should reach out if you experience drenching night sweats that soak through clothing and bedding, sweating accompanied by fever or chills, or sweating that develops suddenly after weeks of stable treatment
Before and After Results Clinical trials have shown: 1015% average body weight reduction with semaglutide (dose-dependent) Up to 1522% average weight reduction in some tirzepatide trials Timeline Expectations: Appetite changes: 14 weeks Visible weight loss: 48 weeks Significant results: 36 months Individual results vary based on dose, adherence, diet, activity level, and metabolic health
Potential benefits: Initial trials of semaglutide showed that the drug not only could effectively control type 2 diabetes, but also led to an average weight loss of 8 to 10 pounds
Rapid weight loss in patients with a history of trauma, restrictive eating, or body image concerns can unmask psychological vulnerabilities
None of that prevents melanocortin receptor pharmacology being a legitimate field, and MC1R signalling in cultured melanocytes is a reasonable thing to study