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These observations suggest a significant contribution of CYPOR to NFT-induced Nrf2 activation in the HepG2 model, but also indicate that other cellular flavoprotein reductases are likely to be involved in the formation of the NFT radical anion and its subsequent activation of Nrf2 and synthesis of GCLC and glutathione

Many reports using polyclonal antisera were unable to detect GLP-1R protein in ventricular cardiomyocytes leaded to the revaluation of those earlier reports

K., Brnden, A

Implications of CT2 in Cancer Unlike the restricted expression in healthy tissue, CT2 is largely expressed in several cancer types also originating from tissues that normally do not express this protein (Lal et al., 2007