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The compounds could potentially be combined, as their mechanisms do not overlap
A single exposure (A) causes a small decrease (less than 3% of normal), in both blood and cytosolic GSH and Cys concentrations, with levels returning to above 99% of normal for all species within the simulated time-span
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Since superoxide anion cannot diffuse across the inner mitochondrial membrane it remains in the matrix which allows it to react with Fe-S groups in mitochondrial proteins resulting in the liberation of ferrous (Fe 2+ ) iron
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