The approach to treatment depends on the individual but may include cognitive behavioral therapy, hearing aids, various types of sound therapy, neuronal modulation, medication, or cochlear implants
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1,2 Cutaneous reactions are the most frequent, with maculopapular exanthemas being the most common type
TOX/TOX2 and NR4A13 function as central regulators that cooperate to establish and maintain an exhaustion program through chromatin remodeling and epigenetic stabilization (90, 91)