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Clinical trials and post-marketing surveillance data consistently show that the following side effects occur commonly, though frequencies vary by product and dose: Nausea (affecting 15-50% of patients, depending on the specific product and dose) Vomiting and diarrhoea Constipation Abdominal pain or discomfort Reduced appetite These gastrointestinal symptoms typically diminish over time as the body adjusts to the medication, usually within 48 weeks

Elshorbagy, A

Endocrinology 153 , 37353746 (2012)

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