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Additional restrictions to the widespread use of GLP-1 RAs and dual GIP/GLP-1 RAs include high treatment costs and limited accessibility in many healthcare systems

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On October 3, 2024, imaging detected a new liver metastasis and progressive enlargement of lung lesions ( Figures 1D, I )

Accessed May 14, 2025, Gonzalez-Martinez F, Johnson-Restrepo B, Quinones LA

Private insurance plans in the United States and employer-sponsored health benefits increasingly include GLP-1 medications in formularies, though often with prior authorization requirements and step therapy protocols