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The honest boundary is that even the coherent pairing is a mechanistic hypothesis with no human validation, so the most defensible research posture is to study the single compound at its documented dose first, and treat any combination as a further, clearly-labelled research question rather than a default
"Thymosin beta4: a multi-functional regenerative peptide." Expert Opin Biol Ther
The number of skin lesions decreased by 51.4%.Graphical Abstract Development and Challenges of Antimicrobial Peptides for Therapeutic Applications Type of study: Number of citations: 402 Year: 2020 Authors: Charles H
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