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This is a critical safety question for patients using semaglutide therapy
Changes in body composition (such as absolute reduction in fat-free body mass) are usually regarded as secondary outcomes, and in clinical practice, they may not be adequately matched with muscle-preserving support measures such as protein intake or resistance exercise
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The AlphaFold prediction for MRP1 closely resembles the bovine MRP1 structure in its bound state, with an RMSD value of 1.707
