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How GHK-Cu Compares to Retinoids, Vitamin C, and Other Anti-Aging Ingredients The 1998 head-to-head trial by Abdulghani measured procollagen synthesis side by side, and the copper-binding peptide outperformed both vitamin C and tretinoin

This leaves you open to oxidative damage caused by reactive oxygen species (aka free radicals)

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Sikirics group has conducted extensive animal toxicology studies demonstrating no observed adverse effects, even at high doses across multiple species