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Shi WJ, Feng LX, Wang X, Huang Y, Wei YF, Huang YY, Ma HJ, Wang W, Xiang MH, Gao LQ
The AAFP recommends injectable therapy when rapid improvement is needed for severe deficiency or serious neurologic involvement
Individuals who may benet from Methylcobalamin injections include those with Vitamin B12 deciency, particularly if due to poor absorption associated with age, gastrointestinal disorders, or following certain surgeries
Supplementation is clinically appropriate for vegans, older adults with reduced stomach acid, people with pernicious anaemia, those on long-term metformin, and individuals with malabsorption conditions such as Crohn's disease