Bromelain is a protease enzyme that's composed of numerous thiol endopeptidases, including protease inhibitors, cellulase, phosphatase, peroxidase, glucosidase, and escharase
Last week at the supplement store I saw a container of 500 mg Acetyl L-Carnitine capsules which had no instructions as to when to take it, which I assume means that it is just as effective with meals as on an empty stomach
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doi:10.1007/s11064-020-03030-1