Contraindications Pregnancy and lactation: individual case reports suggest safety during pregnancy (de Bruyn 2015), however data which mainly include in vivo studies (Xi 2008) are insufficient
The most common symptoms include fatigue, pale or yellow skin, difficulty concentrating, headaches, gastrointestinal upset, depression, and numbness or tingling in the hands or feet
References Hanahan D, Weinberg RA
When semaglutide is injected, it binds to GLP-1 receptors in the brain and digestive system, triggering several weight-loss-supportive effects: Reduces Appetite It signals the brain that you're full, even with smaller portions, helping you eat less without feeling deprived
If fatigue persists beyond this period or worsens, medical review is recommended to identify underlying causes