The simplest way to picture it: GLP-1 tells your gut to slow down, while amylin tells your brain you are full - through a different channel
J Cell Biochem 123(12):18791890 Yaribeygi H, Maleki M, Butler AE, Jamialahmadi T, Sahebkar A (2021) The impact of incretin-based medications on lipid metabolism
These proteins, which are generally membrane crossing, include CD9, CD63, CD81, and CD82 and regulate processes like fusion, migration, and adhesion
While the specific mechanism causing the effects on the gastrointestinal tract are not fully elucidated, studies suggest GLP-1 and its analogues likely exert effects on the vagus nerve and inhibit cholinergic neurotransmission in the gastrointestinal system to prevent movement of the intestine

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