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Across the SURPASS phase 3 programme versus placebo and active comparators, including semaglutide, tirzepatide has shown superior dose-dependent reductions in HbA1c levels up to 2.5% and body weight up to 13%, compared with all comparators [88-91]
It's a prudent measure, especially during the initial phases of a study, to have a source of simple carbohydrates readily available to manage any hypoglycemic events
Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway
GLP-1 medications are contraindicated in severe gastroparesis and should be used cautiously in patients with gastrointestinal disease
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