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What you will learn in this article: Retatrutide is an investigational triple G agonisttargeting GLP-1, GIP, and glucagon receptorscurrently in Phase 3 clinical trials by Eli Lilly
Principle 4: Hydration Prevents Serious Complications Every serious complication in clinical trials involved dehydration
Symptoms include abdominal pain, diarrhea, nausea, vomiting, fever and chills
So, it helps fight against free radicals
Cost-effectiveness of semaglutide in people with obesity and cardiovascular disease without diabetes
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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