berberine and acetyl l carnitine Tanya Malik Chawla | vs Which one should YOU take? Both are metabolic powerhouses, but they work in completely different ways Berberine HCl 1200mg | Gut

The landmark 1998 study by Raun and colleagues described it as "the first selective growth hormone secretagogue," demonstrating potent, dose-dependent GH release in animal models with a clean hormonal profile critically, without the cortisol and prolactin spikes of earlier GHRPs

The animal data showing GH/IGF-1 elevation and bone/lean mass gains comes from aged, often GH-deficient animal models populations with impaired baseline GH axis function

Skin collagen, hydration, elasticity, wrinkles, and scalp and hair parameters improved by 12 weeks of treatment over baseline values and when compared with placebo-control levels

While safety data from this trial is encouraging, the sample size is too small for any meaningful conclusions to be drawn

Toxins (2018)