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Science (1937) 85:3667

Diabetes Care 30 , 16081610 (2007)

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This peptide is highly regarded in the scientific community for its stability and its role in cellular signaling pathways related to tissue remodeling and cytoprotection

Necroptosis can also be materialized as a result of activation of the signaling pathways, due to DNA damage, which leads to the release of apoptosis-related factors from the mitochondrial intermembrane space, followed by the activation of the DNA damagerelated enzyme poly(ADP-ribose) polymerase (PARP) [213]