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In terms of average weight loss and blood sugar reduction in clinical trials, yes tirzepatide consistently outperforms semaglutide
For treatment periods exceeding 1.5 years, the odds ratio jumped to 2.32 (95% CI: 1.49-3.60)
In the SURPASS trial series for type 2 diabetes, tirzepatide achieved hemoglobin A1C reductions of 1.92.6% depending on dose, with many patients reaching non-diabetic glucose levels
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Yes, dietary changes are likely to have the greatest effect on increasing GLP-1 levels
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