If the preclinical data are promising, the drug sponsor can apply for an Investigational New Drug (IND) application to initiate clinical trials in humans
Preclinical studies with BPC-157, which shares the identical active sequence, have demonstrated protective effects against various forms of neural damage
Documentation matters more for research applications
Clinical trial studies will better discover or verify the efficacy, adverse reactions, permeability, persistence, and excretion of TCM drugs
These FeBOs recapitulate several aspects of cellular heterogeneity and complex organization in vivo of the developing human brain (Hendriks et al., 2024), opening an independent avenue to study the human fetal brain in health and disease