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In conclusion, a suite of microbiota-targeted strategies diet, pre/probiotics, FMT, postbiotics, and precision drugs are under active investigation as novel treatments for neurodegenerative diseases

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The good news here is that even after being damaged, the ICC can self-repair 13 14 and the neuroelectrical system in the gut can rewire itself to regain normal ICC function

Emerging evidence suggests protein kinase A mediated phosphorylation of HSD17B13 enhances its interaction with adipose triglyceride lipase, promoting lipolysis and attenuating MASH progression [59]

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