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Glutamate-cysteine ligase (GCL) forms -glutamylcysteine from glutamate and cysteine, after which glutathione synthetase adds glycine

Understanding these systems reveals prospective treatment targets, such as gut microbiota composition adjustment, microbial metabolite supplementation, immune cell control, and neuroimmune signaling pathway interventions [110]

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Many approaches to weight loss, including severe caloric restriction and even some GLP-1 medications, can lead to substantial loss of lean tissue along with fat

Thus, we theorize that there was not an increase in ATP production, as was assumed, and the reactions did not take place in the mitochondria