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Environ Health Perspect 1992

Earlier STEP trials reinforced these findings, showing average weight loss near 15% over 68 weeks when semaglutide was paired with lifestyle guidance

18,19 However, there is a growing body of evidence strongly supporting the notion that NAFLD precedes the development of type 2 diabetes mellitus (T2DM) and metabolic syndrome

Although permanent discontinuation of therapy was recorded in 5.5% of patients, the reasons varied and included elective switches to other incretin-based agents, perceived inadequate efficacy, and patient request