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Protecting muscle mass with oral GLP-1s A major concern with the rapid weight loss seen with GLP-1 therapy is that the body doesnt just lose fat, the weight loss also affects muscle as well

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In summary, elevated levels of inflammatory factors partly initiated by microglia and other recruited immune cells causes a phenotypic switch in astrocytes that contributes to functionally perpetuating inflammation via the release of pro-inflammatory cytokines and recruitment of peripheral immune cells

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International Journal of Cancer