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While none have yet received official approval, ongoing clinical trials may pave the way for targeted treatments in the future

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For example, in a new study, patients who first used a daily topical treatment gel containing 0.1% adapalene and 2.5% benzoyl peroxide for 2-4 weeks before undergoing 3 treatments with Sebacia, spaced 1-2 weeks apart, saw an improvement of 66% at 3 months, as compared to those who had Sebacia alone (in the clinical trials), and showed 49% improvement at 3 months

There is no receptor to desensitise on a fast clock, and no acute spike to time around a meal

Marks are less fine (0.1 mL), so it's a bit less precise for small doses