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Beyond weight management, DA-1726 demonstrated notable improvements in non-invasive liver biomarkers, including significant reductions in liver stiffness, Controlled Attenuation Parameter (CAP) scores, and FibroScan-AST (FAST) scores

Intriguingly, GLP1/GIP had limited efficacy in our PCOS model with more severe metabolic complications, i.e., PWA mice fed HFD, suggesting that in the presence of persistently elevated androgen levels, its beneficial effects might be dampened

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