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Participants with higher baseline NT-proBNP had a similar degree of weight loss but experienced larger reductions in HF-related symptoms and physical limitations with semaglutide than those with lower NT-proBNP, suggesting disease-modifying effects of semaglutide and lending further support for outcome trials of incretin-based therapies in HFpEF

ZBTB1 regulates asparagine synthesis and leukemia cell response to L-asparaginase