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In summary, a large decrease in Tregs under obese conditions may be greatly related to ferroptosis, which may also fall on the classic antioxidant axis x c -GSH-GPX4, serving to induce ferroptosis in activated Tregs in this antioxidant pathway
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(urea cycle) OTC ornithine transcarbamylase deficiency -carbamoyl phosphate synthetase deficiency
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Burruss CP et al
