That may sound strict, but it is practical: poor gut clearance impairs estrogen metabolism and can worsen symptoms even when hormones are replaced
While peptide-based linkers cleaved by lysosomal proteases such as cathepsin B remain the most established approach, their performance can be affected by protease expression variability and extracellular instability
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Thanks to such innovations, anti-aging medicine is shifting from a purely aesthetic focus to a holistic health approach, where outward appearance becomes a reflection of inner balance and optimal bodily function
They may also slow the progression of diabetes-related nephropathy, making them valuable in comprehensive diabetes management (10)