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Increased sexual desire: RECONNECT trial data showed statistically significant gains on the Female Sexual Function Index desire domain

results varied across dose groups and this context is important when interpreting the data GI side effects were the most common adverse events, consistent with the GLP-1 class, and were predominantly mild to moderate in severity, declining over time Small increases in heart rate and gallbladder-related events were also observed, consistent with class effects The trial was of limited duration

Whether people maintain their weight loss on the pill over two, three, or five years remains to be seen

Proteins also increase thermogenesis, which burns more calories during digestion and promotes weight reduction

Why Weight Often Returns After You Stop a GLP-1 When people stop taking a GLP-1, research shows many of the metabolic effects start reversing within weeks, and weight often returns while lost muscle mass does not