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10.7717/peerj.13082 62 LiuW.XuZ.LiH.GuoM.YangT.FengS.et al (2017)
Research shows that insulin-like growth factor 1 acts as an antioxidant and anti-inflammatory inside the blood vessels
One reason may be its role as a cofactor of glutathione peroxidase
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Topiramate blocks the ionotropic glutamate receptors in the trigeminothalamic pathway, as well as sodium and calcium channels with GABA signal enhancement (87)
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