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They develop mostly in midlife at an average age of about 40 years but can occur as early as the late teens or as late as age 80 years

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A key conceptual priority for the field will be to distinguish direct signal transmission from the propagation of ferroptosis susceptibility states, as these processes may reflect fundamentally different modes of tissue-level coordination

doi: Hu, Y., Zheng, S.-L., Ye, X.-L., Shi, J.-N., Zheng, X.-W., Pan, H.-S., Zhang, Y.-W., Yang, X.-L

patients with pre-existing retinopathy should undergo ophthalmologic monitoring