surmount-1 trial tirzepatide non-diabetic weight loss once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 Semaglutide vs. Tirzepatide for Obesity

In my experience, using GH/HGH long-term for too long can cause insulin resistance and lead to gestational diabetes

The much larger, headline-grabbing numbers associated with cagrilintide in the press figures in the low-to-mid 20% range come from Phase 3 trials of CagriSema , the combination with semaglutide, and are company-reported topline results, not standalone-cagrilintide data and not the peer-reviewed Phase 2 result cited above

Choose based on those operational details rather than marketing

Lm reversed gut dysbiosis and restored the abundance of commensal bacteria genera ( Faecalibaculum , Coriobacteriaceae UCG 002, Lactococcus , Negativibacillus , Turicibacter , Ruminiclostridium 6, Parasutterella , Eubacterium xylanophilum group, Ruminococcaceae UCG 010, and Staphylococcus ) which are mainly SCFAs producers resulting in enhanced intestinal barrier integrity

Call your doctor if you feel unwell in addition to having body aches