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Conclusion Mechanisms of cancer resistance mediated by metabolic alterations point to the kynurenine pathway as a critical metabolic axis in the TME that supports cancer cell survival and immune evasion

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The FTIR spectra showed distinctive peaks corresponding to functional groups in the PVA/CH-SeNPs composite, including O-H, C-H, and C-O stretching vibrations

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Notably, NRF2 promoter binding was not determinant of transcriptional response to NRF2 knockdown in A549 and NCI-H460, which was highly correlated between the two models (Fig