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Clinical trials show tirzepatide produces 2025% weight loss in many users, compared to semaglutide's 1518% average
While these medications work through separate pathways, their effects can overlap, particularly regarding appetite suppression and cardiovascular stimulation
Occasional numbness or tingling rare, more common with CJC-1295 at higher doses
Thus, widespread use of GLP-1 RAs may result in widespread public health concerns, particularly in individuals with obesity and low lean muscle mass (OLLMM) and the elderly 40
"This is how regulation works recognising that there is activity that is not in keeping with the safety of the community and taking action to address it." The TGA says its investigations are ongoing
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