doi: 10.1111/jcmm.14393 126 JungEKimJHKimMOLeeSYLeeJ
Monocyte-derived macrophages expand the murine stress erythropoietic niche during the recovery from anemia
Its molecular structure features a stable arrangement that confers resistance to enzymatic degradation in in vitro settings, making it a practical tool for laboratory protocols requiring compound stability over extended incubation periods
IV infusions are time-consuming and have a greater risk of infection and complications due to the potential for blood clots and air bubble formation
Preclinical studies and clinical trials suggest that antioxidants, such as small thiol molecules (N-acetyl-L-cysteine and carbocysteine), antioxidant enzymes (glutathione peroxidases), activators of Nrf2-regulated antioxidant defense system (sulforaphane), and vitamins, for example, C, E, and D, enhance the endogenous antioxidant system and reduce oxidative stress