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Across the studied peptides, the authors reported reduced MMP-9 synthesis, increased Ki-67 and CD98hc expression, and, for AED and AEDG, suppression of caspase-dependent apoptosis that increased during cell-culture aging

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A very clear clinical framing of peptides

Furthermore, as mentioned (Gwyer et al., 2019), BPC 157 inhibits the growth of several tumor lines and can counteract tumor cachexia (Kang et al., 2018), a point combined, as mentioned, with counteracted pro-inflammatory and pro-cachectic cytokines such as IL-6, TNF-, cancer cachexiarelated pathways expression (i.e., FoxO3a, p-AKT, p-mTOR, and P-GSK-3) (Kang et al., 2018)