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Patients with type 2 diabetes and obesity

At pH 3.88 (acetate form), accelerated stability testing shows degradation to 21.3% remaining after extended heat stress, while at pH 8.42 (sodium salt), 96.7% remains under identical conditions

Common Community-Reported Side Effects Nausea, vomiting, diarrhea, constipation (worst during escalation steps)

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Early, in-depth review article that evaluates the similarities and differences between short-acting and long-acting GLP-1R agonists in terms of glucose-lowering efficacy and adverse effects, and discusses the possibilities for utilizing these agents for individualized treatment of T2DM