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Simple timing framework Baseline Discuss baseline labs before starting or escalating, especially with diabetes, kidney disease, gallbladder history, eating-disorder history, or major calorie restriction

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Yin Q, Ma Y, Hong Y, Hou X, Chen J, Shen C, Sun M, Shang Y et al (2014) Lycopene attenuates insulin signaling deficits, oxidative stress, neuroinflammation, and cognitive impairment in fructose-drinking insulin resistant rats

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Controlled Release 282 , 6275 (2018)