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GH levels are controlled by the release of GHRH and GHIH (also known as somatostatin) from the hypothalamus
Tirzepatide has demonstrated superior efficacy in both weight loss and blood glucose control compared to semaglutide (Aronne et al., 2025), highlighting the therapeutic potential of multi-agonist strategies
This also includes medication, consultations, follow-ups, lifestyle guidance, and around-the-clock access to providers
Previously, the only evidenced and effective long-term treatment for obesity was weight-loss surgery where we have evidence that surgery is capable of giving long-term weight loss for 20 years or so
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