if confirmed, do not start Semaglutide treatment
The combination is the point
When the body releases the GLP-1 hormone, it gives you a feeling of fullness and signals you to stop eating
In June 2024, tirzepatide (Zepbound, Mounjaro) was added to the FAAs Acceptable Weight Loss Medications category, clearing the path to general eligibility medical certification for pilots and ATCS
Critically, a positive feedback loop emerges between accumulated long-chain acylcarnitines and excessive ROS: these acylcarnitines inhibit electron transport chain complex III, inducing ROS overproduction, whereas ROS suppresses CPT2 activity, preventing further metabolism of long-chain acylcarnitines [55, 135,136,137,138]