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Trials are ordered chronologically and added sequentially, so that each line represents the updated pooled estimate after inclusion of each additional study
Following this period, all persons enrolled in the trial stopped the drug (or the placebo) for two months, in what was referred to as a washout period. What would have been considered a positive result for this trial
Because of the clear weight loss risks, the agencys Wegovy pregnancy warning is slightly more stringent than the warning on Ozempic
Results Baseline characteristics We identified 42,816 subjects treated with metformin in combination with either GLP-1 RAs (n = 16,723) or DPP-4is (n = 26,093)
