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Importantly, AOD-9604 does not bind to growth hormone receptors, which is why it lacks the glucose-elevating and IGF-1-stimulating effects of full-length growth hormone

When your body loses fluids through sweating, illness, exercise, or simply not drinking enough water, your blood volume decreases slightly

Precise efficacy will differ and additional studies are necessary before broad application

In 2025, it was also approved to treat chronic kidney disease in patients with Type 2 diabetes

Evernorth's study found that more than 50% of those who take GLP-1s stop doing so within 12 months, limiting the data available on the medications for longer periods