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Like other chronic diseases, we need a range of treatment options to address the individual needs of people with obesity, such as their own specific response to treatment. 1 The most common adverse effects were gastrointestinal, including nausea, vomiting, diarrhea, and constipation that were mild to moderate in severity

Biological & Pharmaceutical Bulletin 31 (9): 16739

Metabolism 55 , 12861292 (2006)

You might also notice more headaches, irritability, or even mouth sores

Denature: To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated