After the formation of an epoxyallylic radical, the enzyme hydroperoxide lyase, which should be more accurately termed a hemiacetal synthase, converts the epoxy intermediate into a vinyl ether and thence to a short-lived hemiacetal, which spontaneously decomposes into two short chain fragments, i.e., cis -3-hexenal and 12oxo- cis -9-dodecenoic acid, though the positions and geometry of the double bonds may change by chemical or enzymatic isomerization
Long-term acid reflux medicines can block absorption
10.1007/s00253-020-10920-5 41 LiF.DaiL.NiuJ
While these findings offer reassurance in cases of inadvertent exposure to GLP-1 medications during the first trimester of pregnancy, larger trials are needed for more conclusive results
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